These highlights do not contain all the information needed to use Depakote securely and properly. See entire prescribing data for Depakote.
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Because these reactions are documented voluntarily from the populace of uncertain sizing, It isn't always probable to reliably estimate their frequency or create a causal relationship to drug publicity.
All Ladies of childbearing age (which include girls from the beginning of puberty) should discuss for their healthcare supplier about employing other probable therapies in lieu of Depakote. If the choice is produced to employ Depakote, you should use efficient beginning Handle (contraception).
Usually do not drive a vehicle, run perilous machinery, or do unsafe activities until finally you know the way Depakote impacts you. Depakote can sluggish your contemplating and motor abilities and could impact your eyesight.
Never drink Liquor although having Depakote. Depakote and Alcoholic beverages can impact each other causing Unwanted side effects for instance sleepiness and dizziness.
The presence of other clinical challenges might have an effect on the use of this medicine. You should definitely explain to your medical doctor When you have another health care troubles, Specifically:
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Concurrent usage of valproate and amitriptyline has rarely been linked to toxicity. Checking of amitriptyline ranges really should be thought of for patients taking valproate concomitantly with amitriptyline. Consideration needs to be provided to reducing the dose of amitriptyline/nortriptyline inside the presence of valproate.
1 The subsequent adverse reactions transpired in a minimum of five% of Depakote-handled individuals and at click here an equivalent or better incidence for placebo than for Depakote: flu syndrome and pharyngitis.
This medication is usually prescribed for other takes advantage of. Request your health care provider or pharmacist To find out more.
1.two Epilepsy Depakote is indicated as monotherapy and adjunctive therapy within the procedure of individuals with advanced partial seizures that happen both in isolation or in Affiliation with other types of seizures. Depakote is likewise indicated to be used as sole and adjunctive therapy inside the cure of simple and complex absence seizures, and adjunctively in sufferers with various seizure sorts that come with absence seizures.
This is very important for Girls setting up a pregnancy and for ladies within the onset of puberty; option therapeutic alternatives must be regarded for these clients [see Boxed Warning and Use in Precise Populations (8.one)]. To prevent major seizures, valproate should not be discontinued abruptly, as this can precipitate status epilepticus with ensuing maternal and fetal hypoxia and danger to everyday living. Proof implies that folic acid supplementation previous to conception And through the primary trimester of pregnancy decreases the danger for congenital neural tube defects in the general population. It is not known whether or not the risk of neural tube defects or lessened IQ during the offspring of ladies getting valproate is reduced by folic acid supplementation. Dietary folic acid supplementation both of those previous to conception and during pregnancy ought to be routinely advised for patients applying valproate.
As a monotherapy and adjunctive therapy to handle complicated partial seizures in Grownup and pediatric individuals aged ten and older.